Nephrotic Syndrome with Thrombocytopenia, Lymphadenopathy, Systemic Inflammation, and Splenomegaly

Systemic lupus erythematosus-nephrotic syndrome and mediastinal lymphadenopathy mimicking lymphoma.

Transient lymphadenopathy secondary to nephrotic syndrome.

Mediastinal lymphadenomegaly secondary to hypervolemia is an underdiagnosed tomographic finding. Herein we describe, in a patient with normal cardiac function, findings of pulmonary congestion associated to lymph node enlargement. The nephrotic syndrome causing hypoalbuminemia, low plasma colloid osmotic pressure and augmented transcapillary fluid leakage was the probable cause of the radiologi...

Kimura's Disease: A Rare Cause of Nephrotic Syndrome with Lymphadenopathy.

Kimura's disease is a rare condition and typically presents as non-tender subcutaneous swellings in the head and neck region, usually in the pre-auricular and submandibular areas. It is associated with lymphadenopathy (both local and distal), marked peripheral eosinophilia, and an elevated IgE level. It can easily be mistaken for a malignant disorder. Fine needle aspiration can be misleading, a...

Atypical hyaline vascular-type castleman's disease with thrombocytopenia, anasarca, fever, and systemic lymphadenopathy.

Recently, atypical Castleman's disease (CD) was reported in Japan. This disease is considered as TAFRO syndrome or non-idiopathic plasmacytic lymphadenopathy (IPL), a constellation of clinical symptoms, namely, thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly without hyper-γ-globulinemia. Histopathologically, this disease is similar to hyaline vascular (HV)-type CD. Here,...

Minimal change nephrotic syndrome associated with systemic lupus erythematosus

Sir, In patients with nephrotic syndrome associated with systemic lupus erythematosus (SLE), the most common histological findings on renal biopsy are diffuse proliferative lupus nephritis (WHO class IV) and membranous lupus nephritis (WHO class V). We report a case of SLE with nephrotic proteinuria due to minimal change nephrotic syndrome (MCNS). In 1995, SLE was diagnosed in a 29-year-old Jap...